Diclazepam   (Ro5-3448),   also known as chlorodiazepam and 2′-chloro-diazepam,   is a benzodiazepine and functional analog of diazepam.   It was first synthesized by Leo Sternbach and his team at Hoffman-La Roche in 1960.   It is not currently approved for use as a medication,   but rather sold as an unscheduled substance.   Efficacy and safety have not been tested in humans.

In animal models,   its effects are similar to diazepam,   possessing long-acting anxiolytic,   anticonvulsant,   hypnotic,   sedative,  skeletal muscle relaxant,   and amnestic properties.